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Dendritic Polyglycerol Amine (dPGA)
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Dendritic Polyglycerol Amine (dPGA)

DendroTEK

Regular price $115.00

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Dendritic Polyglycerol Amine (dPGA) is a synthetic polymer used for coating glass or plastic cell culture substratum. It promotes robust cell adhesion across a wide range of cell types, offering a consistent and reliable alternative to traditional coatings. With defined composition and animal-free origin, dPGA minimizes variability and supports reproducible, scalable workflows in both research and manufacturing environments.  

This product is supplied as a sterile-filtered aqueous solution at concentrations of 5 mg/mL, 10 mg/mL, or 50 mg/mL. For coating applications, we recommend diluting to a working concentration of 0.05–0.1 mg/mL. 

Product Data sheet and Coating Protocol available here.

Safety Date Sheet (SDS) available here.

dPGA supports iPSC-derived cortical neurons

Clément J-P et al. “Dendritic Polyglycerol Amine: An Enhanced Substrate to Support Long-Term Neural Cell Culture.” ASN Neuro 2022

Astrocyte-Neuron-Microglia co-culture with dPGA

Keaney J et al. “Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways.” Journal of Neuroinflammation 2024

dPGA as a primary coating for better Matrigel® performance

Thiry L et al. “Optimization of Long-Term Human iPSC-Derived Spinal Motor Neuron Culture Using a Dendritic Polyglycerol Amine-Based Substrate.” ASN Neuro 2022

Better MEA coverage with DendroTEK dPGA

Thiry L et al. “Optimization of Long-Term Human iPSC-Derived Spinal Motor Neuron Culture Using a Dendritic Polyglycerol Amine-Based Substrate.” ASN Neuro 2022

Reduced clumping in iPSC-derived midbrain neurons

Unpublished data shared by Yanping Zhu, Centre for High Throughput Chemical Biology, Simon Fraser University

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